Non-alcoholic fatty liver – Perhaps not so benign

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Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease describes a range of conditions caused by a build-up of fat within liver cells. It is very common and in many cases is linked to being obese or overweight. Most people with non-alcoholic fatty liver disease do not develop serious liver problems. In some people, the build-up of fat in the liver can lead to serious liver disease. However, all people with non-alco...

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Non-Alcoholic Fatty Liver Disease

Results: The term “non-alcoholic fatty liver disease” covers cases of a wide spectrum of severity, ranging from bland fatty liver without any inflammation and with little or no tendency to progress all the way to non-alcoholic steato hepatitis (NASH) with inflammatory reactions and hepatocyte damage, with or without fibrosis. Some 5% to 20% of patients with NAFLD develop NASH, which undergoes a...

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Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease describes a range of conditions caused by a build-up of fat within liver cells. It is very common and in many cases is linked to being obese or overweight. Most people with non-alcoholic fatty liver disease do not develop serious liver problems. In some people, the build-up of fat in the liver can lead to serious liver disease. However, all people with non-alco...

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Non-alcoholic fatty liver disease

are also associated with a greater risk of NAFLD and NASH at any given body mass index, and preliminary evidence suggests greater liver fat content in certain ethnicities that are also known to be at increased risk of type 2 diabetes. Preliminary evidence suggests a genetic predisposition to hepatic accumulation of fat in some people through the PNP3A gene. Such people may not necessarily displ...

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ژورنال

عنوان ژورنال: Journal of Hepatology

سال: 2015

ISSN: 0168-8278

DOI: 10.1016/j.jhep.2015.02.005